Police chased cars through Blackburn Road yesterday evening at around 8pm.
While the police were in pursuit, two cars crashed at the junction of Blackburn Road and Halliwell Road, leaving one car without a wheel.
A black Range Rover and silver Ford Fiesta were caught in the crash and a number of police cars rushed to the scene.
The Bolton News understands that at least one driver made off from the scene.
Eyewitnesses said there was a third car involved in the chase, but was not caught up in the chaos at the junction.
Greater Manchester Police have been contacted for a response.